Pattern of subtypes of acute lymphoblastic leukemia in India

D. M. Kamat; R. Gopal; S. H. Advani; C. N. Nair; Ashok Kumar; Tapan Saikia; J. J. Nadkarni; J. S. Nadkarni

doi:10.1016/0145-2126(85)90315-7

Pattern of subtypes of acute lymphoblastic leukemia in India

D. M. Kamat
, R. Gopal
, S. H. Advani
, C. N. Nair
, Ashok Kumar
, Tapan Saikia
, J. J. Nadkarni
, J. S. Nadkarni

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (Slg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of Slg. Ia antigen was detected in 44.4% of ALL and 64% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.

Original language	English (US)
Pages (from-to)	927-934
Number of pages	8
Journal	Leukemia Research
Volume	9
Issue number	7
DOIs	https://doi.org/10.1016/0145-2126(85)90315-7
State	Published - 1985
Externally published	Yes

Keywords

ALL
C-ALL
T-ALL

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

Access to Document

10.1016/0145-2126(85)90315-7

Cite this

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title = "Pattern of subtypes of acute lymphoblastic leukemia in India",

abstract = "Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (Slg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33\% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of Slg. Ia antigen was detected in 44.4\% of ALL and 64\% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.",

keywords = "ALL, C-ALL, T-ALL",

author = "Kamat, \{D. M.\} and R. Gopal and Advani, \{S. H.\} and Nair, \{C. N.\} and Ashok Kumar and Tapan Saikia and Nadkarni, \{J. J.\} and Nadkarni, \{J. S.\}",

year = "1985",

doi = "10.1016/0145-2126(85)90315-7",

language = "English (US)",

volume = "9",

pages = "927--934",

journal = "Leukemia Research",

issn = "0145-2126",

publisher = "Elsevier Ltd",

number = "7",

}

TY - JOUR

T1 - Pattern of subtypes of acute lymphoblastic leukemia in India

AU - Kamat, D. M.

AU - Gopal, R.

AU - Advani, S. H.

AU - Nair, C. N.

AU - Kumar, Ashok

AU - Saikia, Tapan

AU - Nadkarni, J. J.

AU - Nadkarni, J. S.

PY - 1985

Y1 - 1985

N2 - Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (Slg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of Slg. Ia antigen was detected in 44.4% of ALL and 64% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.

AB - Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (Slg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of Slg. Ia antigen was detected in 44.4% of ALL and 64% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.

KW - ALL

KW - C-ALL

KW - T-ALL

UR - https://www.scopus.com/pages/publications/0021889032

UR - https://www.scopus.com/pages/publications/0021889032#tab=citedBy

U2 - 10.1016/0145-2126(85)90315-7

DO - 10.1016/0145-2126(85)90315-7

M3 - Article

C2 - 3894805

AN - SCOPUS:0021889032

SN - 0145-2126

VL - 9

SP - 927

EP - 934

JO - Leukemia Research

JF - Leukemia Research

IS - 7

ER -

Pattern of subtypes of acute lymphoblastic leukemia in India

Abstract

Keywords

ASJC Scopus subject areas

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