Abstract
Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (Slg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of Slg. Ia antigen was detected in 44.4% of ALL and 64% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.
Original language | English (US) |
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Pages (from-to) | 927-934 |
Number of pages | 8 |
Journal | Leukemia Research |
Volume | 9 |
Issue number | 7 |
DOIs | |
State | Published - 1985 |
Externally published | Yes |
Keywords
- ALL
- C-ALL
- T-ALL
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research