Pattern of subtypes of acute lymphoblastic leukemia in India

D. M. Kamat, R. Gopal, S. H. Advani, C. N. Nair, Ashok Kumar, Tapan Saikia, J. J. Nadkarni, J. S. Nadkarni

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (Slg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of Slg. Ia antigen was detected in 44.4% of ALL and 64% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.

Original languageEnglish (US)
Pages (from-to)927-934
Number of pages8
JournalLeukemia Research
Volume9
Issue number7
DOIs
StatePublished - 1985
Externally publishedYes

Keywords

  • ALL
  • C-ALL
  • T-ALL

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Pattern of subtypes of acute lymphoblastic leukemia in India'. Together they form a unique fingerprint.

Cite this