Abstract
Angioplasty produces its effect primarily by mechanical deformation of the arterial wall. Significant changes are produced acutely, including intimal splitting, intimal-medial dehiscence, and medical necrosis. Repair of the vessel is generally complete, with enlargement of the lumen due in part to permanent stretching of the media. Less well understood, although perhaps equally important, are the physiologic changes produced in the vessel wall by angioplasty. Disruption of the vessel's nutrient supply and prostaglandin metabolism may affect the long-term morphologic outcome of the procedure. Aspirin may produce long-term benefits by inhibiting local prostaglandin metabolism.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 241-245 |
| Number of pages | 5 |
| Journal | Seminars in Interventional Radiology |
| Volume | 1 |
| Issue number | 4 |
| State | Published - 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
Pathophysiology of transluminal angioplasty. / Cragg, A.; Castaneda-Zuniga, W. R.; Amplatz, K.
In: Seminars in Interventional Radiology, Vol. 1, No. 4, 1984, p. 241-245.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pathophysiology of transluminal angioplasty
AU - Cragg, A.
AU - Castaneda-Zuniga, W. R.
AU - Amplatz, K.
PY - 1984
Y1 - 1984
N2 - Angioplasty produces its effect primarily by mechanical deformation of the arterial wall. Significant changes are produced acutely, including intimal splitting, intimal-medial dehiscence, and medical necrosis. Repair of the vessel is generally complete, with enlargement of the lumen due in part to permanent stretching of the media. Less well understood, although perhaps equally important, are the physiologic changes produced in the vessel wall by angioplasty. Disruption of the vessel's nutrient supply and prostaglandin metabolism may affect the long-term morphologic outcome of the procedure. Aspirin may produce long-term benefits by inhibiting local prostaglandin metabolism.
AB - Angioplasty produces its effect primarily by mechanical deformation of the arterial wall. Significant changes are produced acutely, including intimal splitting, intimal-medial dehiscence, and medical necrosis. Repair of the vessel is generally complete, with enlargement of the lumen due in part to permanent stretching of the media. Less well understood, although perhaps equally important, are the physiologic changes produced in the vessel wall by angioplasty. Disruption of the vessel's nutrient supply and prostaglandin metabolism may affect the long-term morphologic outcome of the procedure. Aspirin may produce long-term benefits by inhibiting local prostaglandin metabolism.
UR - http://www.scopus.com/inward/record.url?scp=0021671466&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021671466&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0021671466
VL - 1
SP - 241
EP - 245
JO - Seminars in Interventional Radiology
JF - Seminars in Interventional Radiology
SN - 0739-9529
IS - 4
ER -