TY - JOUR
T1 - Pathophysiology of prediabetes
AU - Abdul-Ghani, Muhammad A.
AU - DeFronzo, Ralph A.
PY - 2009
Y1 - 2009
N2 - The term prediabetes refers to subjects with impaired fasting glucose and/or impaired glucose tolerance who are at increased risk for type 2 diabetes mellitus. Although both types of patients are at increased risk for developing type 2 diabetes mellitus and cardiovascular disease, they manifest distinct metabolic abnormalities. In this article, we summarize the metabolic abnormalities that characterize each state and the contribution of these metabolic abnormalities to the increased risk of diabetes and cardiovascular disease.
AB - The term prediabetes refers to subjects with impaired fasting glucose and/or impaired glucose tolerance who are at increased risk for type 2 diabetes mellitus. Although both types of patients are at increased risk for developing type 2 diabetes mellitus and cardiovascular disease, they manifest distinct metabolic abnormalities. In this article, we summarize the metabolic abnormalities that characterize each state and the contribution of these metabolic abnormalities to the increased risk of diabetes and cardiovascular disease.
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U2 - 10.1007/s11892-009-0032-7
DO - 10.1007/s11892-009-0032-7
M3 - Review article
C2 - 19490820
AN - SCOPUS:66149124911
SN - 1534-4827
VL - 9
SP - 193
EP - 199
JO - Current Diabetes Reports
JF - Current Diabetes Reports
IS - 3
ER -