Pathophysiology of chest trauma

John H Calhoon, J. K. Trinkle

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Recent information indicates that there is a complex cellular and molecular generic response to injury that can lead to multi-organ failure. For many years, basic physiology and biochemistry were considered to be the systemic mechanisms to injury, but now it is known that subcellular and molecular events are the keys to unlocking the secrets of the body's response to trauma. The interaction of the endothelial cell with neutrophils and platelets to produce cytokines, free radicals, and upregulating adhesion molecules is especially significant.

Original languageEnglish (US)
Pages (from-to)199-211
Number of pages13
JournalChest Surgery Clinics of North America
Volume7
Issue number2
StatePublished - 1997

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Thorax
Wounds and Injuries
Biochemistry
Free Radicals
Neutrophils
Blood Platelets
Endothelial Cells
Cytokines

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Pathophysiology of chest trauma. / Calhoon, John H; Trinkle, J. K.

In: Chest Surgery Clinics of North America, Vol. 7, No. 2, 1997, p. 199-211.

Research output: Contribution to journalArticle

Calhoon, JH & Trinkle, JK 1997, 'Pathophysiology of chest trauma', Chest Surgery Clinics of North America, vol. 7, no. 2, pp. 199-211.
Calhoon, John H ; Trinkle, J. K. / Pathophysiology of chest trauma. In: Chest Surgery Clinics of North America. 1997 ; Vol. 7, No. 2. pp. 199-211.
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