Patologicheskie tipy dykhaniia pri vozdeistvii ostroi gipoksii.

Translated title of the contribution: Pathological types of breathing during acute hypoxia

N. S. Akopian, N. V. Sarkisian, N. I. Adamian, K. V. Bagdasarian, Armen N Akopian

Research output: Contribution to journalArticle

Abstract

Different breathing pathologies (apneusis, gasping, Cheyne-Stokes breathing and Kussmaul breathing) were observed in anaesthetized rabbits and rats exposed to hypoxia at the altitude of 7500-8000 meters. Dominance of the high-voltage slow EKG activity (the delta-wave type) suggested deterioration of the brain functioning. Registration of impulse activities of the inspiration and expiration breathing neurons in medulla oblongata revealed a higher tolerance of the inspiration neurons to severe hypoxia which is attributed to the metabolic specifics and functional heterogeneity of these neurons. Character of the neuron impulsation is indicative of the reflectory effects of hemo- and mechanoreceptors, and the direct effects of different humoral substances resulting in impairment of the central control of pacemakers and breathing pathologies. It appears that various breathing pathologies in altitude chambers and mountains are triggered by the hypoxic factor. However, no dependence was established either between the initial breathing rhythm (before "ascent") and various types of breathing at the "altitude" or these types of breathing and magnitude of hypoxia.

Original languageUndefined
Pages (from-to)32-37
Number of pages6
JournalAviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine
Volume36
Issue number1
StatePublished - 2002
Externally publishedYes

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Neurons
Respiration
Pathology
Pacemakers
Electrocardiography
Deterioration
Rats
Brain
Altitude Sickness
Hypoxia
Medulla Oblongata
Mechanoreceptors
Electric potential
Rabbits

Cite this

Patologicheskie tipy dykhaniia pri vozdeistvii ostroi gipoksii. / Akopian, N. S.; Sarkisian, N. V.; Adamian, N. I.; Bagdasarian, K. V.; Akopian, Armen N.

In: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine, Vol. 36, No. 1, 2002, p. 32-37.

Research output: Contribution to journalArticle

Akopian, N. S. ; Sarkisian, N. V. ; Adamian, N. I. ; Bagdasarian, K. V. ; Akopian, Armen N. / Patologicheskie tipy dykhaniia pri vozdeistvii ostroi gipoksii. In: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 2002 ; Vol. 36, No. 1. pp. 32-37.
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