Pathologic features of various ventilatory strategies

J. J. Coalson; R. A. DeLemos

Pathologic features of various ventilatory strategies

J. J. Coalson, R. A. DeLemos

Pathology

Research output: Contribution to journal › Article › peer-review

Abstract

Original language	English
Pages (from-to)	108-116
Number of pages	9
Journal	Acta Anaesthesiologica Scandinavica, Supplement
Volume	33
Issue number	90
State	Published - 1989

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'Pathologic features of various ventilatory strategies'. Together they form a unique fingerprint.

Cite this

@article{b4eb46d385d944598c86300a84630edb,

title = "Pathologic features of various ventilatory strategies",

abstract = "Five pathologic findings have been found to be associated with ventilatory-induced lung injury in the premature baboon model of hyaline membrane disease. They are: (1) tracheal and major bronchial lesions, (2) small airway changes, (3) inflation pattern aberrations, (4) bronchoalveolar hemorrhage, and (5) air leak problems. The use of immediate high frequency oscillatory ventilation (HFOV) prevents the bronchiolar overdistension (small airway), atelectasis (inflation pattern), and air leak problems. The lesions in the trachea and large bronchi of prematures all show injury secondary to prolonged intubation, but after HFOV the lesions are no worse than those seen in PPV-treated tracheas. HFOV does increase the incidence of bronchoalveolar hemorrhages, and this lesion plus some of the non-pulmonary complications will require further investigation.",

author = "Coalson, {J. J.} and DeLemos, {R. A.}",

year = "1989",

language = "English",

volume = "33",

pages = "108--116",

journal = "Acta Anaesthesiologica Scandinavica, Supplement",

issn = "0515-2720",

publisher = "Blackwell Munksgaard",

number = "90",

}

TY - JOUR

T1 - Pathologic features of various ventilatory strategies

AU - Coalson, J. J.

AU - DeLemos, R. A.

PY - 1989

Y1 - 1989

N2 - Five pathologic findings have been found to be associated with ventilatory-induced lung injury in the premature baboon model of hyaline membrane disease. They are: (1) tracheal and major bronchial lesions, (2) small airway changes, (3) inflation pattern aberrations, (4) bronchoalveolar hemorrhage, and (5) air leak problems. The use of immediate high frequency oscillatory ventilation (HFOV) prevents the bronchiolar overdistension (small airway), atelectasis (inflation pattern), and air leak problems. The lesions in the trachea and large bronchi of prematures all show injury secondary to prolonged intubation, but after HFOV the lesions are no worse than those seen in PPV-treated tracheas. HFOV does increase the incidence of bronchoalveolar hemorrhages, and this lesion plus some of the non-pulmonary complications will require further investigation.

AB - Five pathologic findings have been found to be associated with ventilatory-induced lung injury in the premature baboon model of hyaline membrane disease. They are: (1) tracheal and major bronchial lesions, (2) small airway changes, (3) inflation pattern aberrations, (4) bronchoalveolar hemorrhage, and (5) air leak problems. The use of immediate high frequency oscillatory ventilation (HFOV) prevents the bronchiolar overdistension (small airway), atelectasis (inflation pattern), and air leak problems. The lesions in the trachea and large bronchi of prematures all show injury secondary to prolonged intubation, but after HFOV the lesions are no worse than those seen in PPV-treated tracheas. HFOV does increase the incidence of bronchoalveolar hemorrhages, and this lesion plus some of the non-pulmonary complications will require further investigation.

UR - http://www.scopus.com/inward/record.url?scp=0024527193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024527193&partnerID=8YFLogxK

M3 - Article

C2 - 2648728

VL - 33

SP - 108

EP - 116

JO - Acta Anaesthesiologica Scandinavica, Supplement

JF - Acta Anaesthesiologica Scandinavica, Supplement

SN - 0515-2720

IS - 90

ER -