Para-aminohippurate and Tetraethylammonium Transport in Fragments of Rat Renal Cortex

Herzl Goldin, Marianne Zmudka, Fermin Tio, Angelina Vasquez, Harry G. Preuss

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

To develop a simple in vitro procedure which, compared to slices, yields less variation in organic anion and cation transport, we used fragments of renal cortex. Each fragment contained 11–15 glomeruli and, after 90 min of incubation, showed normal brush border and well-preserved epithelium. With this technique, there was less variation in transport studies within a given experiment, and fragments responded in the same manner as slices to addition of acetate and serum to the medium.

Original languageEnglish (US)
Pages (from-to)692-696
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume144
Issue number2
DOIs
StatePublished - Nov 1973
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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