Pancreatic transplantation: Radiologic evaluation of vascular complications

Jon F. Snider, David W. Hunter, Christopher C. Kuni, Wilfrido R. Castaneda-Zuniga, Janis Gissel Letourneau

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Transplantation of the pancreas is an increasingly common therapeutic option for preventing or delaying complications of type I diabetes mellitus. The authors studied the relative roles of various radiologic examinations in diagnosing vascular complications in these grafts, including arterial and venous thrombosis, stenosis, and anastomotic leak (the most common vascular factors that necessitate pancreatectomy of the transplant), as defined with pathologic or arteriographic data. The results of 78 scintigraphic flow studies, 40 abdominal and pelvic computed tomographic (CT) scans, 27 sonograms, and eight color Doppler studies were evaluated in 52 patients who received a total of 27 cadaveric and 26 living-donor grafts over a 12-year period. These results were correlated with the data from 45 gross and microscopic pathologic studies and 37 arteriograms to determine their relative value in enabling detection of graft thrombosis and other vascular complications. Scintigraphy, CT, sonography, and color Doppler were all sensitive in detection of generalized graft abnormalities but lacked specificity in defining the underlying etiologic factors.

Original languageEnglish (US)
Pages (from-to)749-753
Number of pages5
JournalRadiology
Volume178
Issue number3
DOIs
Publication statusPublished - Mar 1991

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Keywords

  • Computed tomography (CT), comparative studies
  • Pancreas, CT, 770.1211
  • Pancreas, US studies, 770.1298
  • Pancreas, radionuclide studies, 77.1299
  • Pancreas, transplantation, 770.458, 770.91
  • Radionuclide imaging, comparative studies

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Snider, J. F., Hunter, D. W., Kuni, C. C., Castaneda-Zuniga, W. R., & Letourneau, J. G. (1991). Pancreatic transplantation: Radiologic evaluation of vascular complications. Radiology, 178(3), 749-753. https://doi.org/10.1148/radiology.178.3.1994413