Pancreatic fluid collections: Clinical manifestations, diagnostic evaluation and management

Chandraprakash Umapathy, Mahesh Gajendran, Rupinder Mann, Umesha Boregowda, Thimmaiah Theethira, Sherif Elhanafi, Abhilash Perisetti, Hemant Goyal, Shreyas Saligram

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Pancreatic fluid collections (PFC), including pancreatic pseudocysts and walled-off pancreatic necrosis, are a known complication of severe acute pancreatitis. A majority of the PFCs remain asymptomatic and resolve spontaneously. However, some PFCs persist and can become symptomatic. Persistent PFCs can also cause further complications such as the gastric outlet, intestinal, or biliary obstruction and infection. Surgical interventions are indicated for the drainage of symptomatic sterile and infected PFCs. Management of PFCs has evolved from a primarily surgical or percutaneous approach to a less invasive endoscopic approach. Endoscopic interventions are associated with improved outcomes with lesser chances of complications, faster recovery time, and lower healthcare utilization. Endoscopic ultrasound-guided drainage of PFCs using lumen-apposing metal stents has become the preferred approach for the management of symptomatic and complicated PFCs.

Original languageEnglish (US)
Article number100986
Issue number11
StatePublished - Nov 2020
Externally publishedYes


  • Lumen-apposing metal stents
  • Pancreatic fluid collections
  • Pancreatic pseudocysts
  • Walled-off pancreatic necrosis

ASJC Scopus subject areas

  • General Medicine


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