TY - JOUR
T1 - Pancreatic cancer
T2 - can we screen? How should we stage?
AU - Parikh, A. A.
AU - Lowy, A. M.
PY - 1999/4
Y1 - 1999/4
N2 - Pancreatic cancer remains a deadly disease, with few patients surviving 5 years following diagnosis. Surgical resection remains the only treatment associated with the potential for cure; however, most patients have locally advanced or metastatic disease at presentation and thus are not surgical candidates. Advances in imaging technologies, biochemistry, and molecular genetics have raised hopes of improving the outcome for patients with pancreatic cancer through earlier and more accurate diagnosis. As our knowledge of the genetics of pancreatic cancer has increased, the possibility of screening to identify patients at risk to develop the disease also holds promise. This review focuses on the utility of current modalities to screen for pancreatic cancer as well as the most accurate and expedient methods to stage the disease.
AB - Pancreatic cancer remains a deadly disease, with few patients surviving 5 years following diagnosis. Surgical resection remains the only treatment associated with the potential for cure; however, most patients have locally advanced or metastatic disease at presentation and thus are not surgical candidates. Advances in imaging technologies, biochemistry, and molecular genetics have raised hopes of improving the outcome for patients with pancreatic cancer through earlier and more accurate diagnosis. As our knowledge of the genetics of pancreatic cancer has increased, the possibility of screening to identify patients at risk to develop the disease also holds promise. This review focuses on the utility of current modalities to screen for pancreatic cancer as well as the most accurate and expedient methods to stage the disease.
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U2 - 10.1007/s11894-996-0017-5
DO - 10.1007/s11894-996-0017-5
M3 - Review article
C2 - 10980945
AN - SCOPUS:0033107654
SN - 1522-8037
VL - 1
SP - 166
EP - 174
JO - Current Gastroenterology Reports
JF - Current Gastroenterology Reports
IS - 2
ER -