Pain management in patients with chronic kidney disease

Phuong Chi T. Pham, Edgar Toscano, Phuong Mai T. Pham, Phuong Anh T. Pham, Son V. Pham, Phuong Thu T. Pham

Research output: Contribution to journalReview articlepeer-review

43 Scopus citations


Pain has been reported to be a common problem in the general population and end-stage renal disease (ESRD) patients. Although similar data for pre-ESRD patients are lacking, we recently reported that the prevalence of pain is also very high (>70%) among pre-ESRD patients at a Los Angeles County tertiary referral centre. The high prevalence of pain in the CKD population is particularly concerning because pain has been shown to be associated with poor quality of life. Of greater concern, poor quality of life, at least in dialysis patients, has been shown to be associated with poor survival. We herein discuss the pathophysiology of common pain conditions, review a commonly accepted approach to the management of pain in the general population, and discuss analgesic-induced renal complications and therapeutic issues specific for patients with reduced renal function.

Original languageEnglish (US)
Pages (from-to)111-118
Number of pages8
JournalNDT Plus
Issue number2
StatePublished - Apr 2009
Externally publishedYes


  • Analgesics
  • Chronic kidney disease
  • Opioids
  • Pain

ASJC Scopus subject areas

  • Nephrology
  • Transplantation


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