Packaging of non-coding RNAs into herpesvirus virions: Comparisons to coding RNAs

Melanie A. Amen, Anthony Griffiths

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The herpesviruses are a family of large DNA viruses capable of establishing lifelong infections. Recent reports have shown that herpesviruses package non-coding RNA into virions; this follows earlier observations showing that coding RNAs are detected in virions. Packaging RNAs allows for their function immediately after virus entry and in the absence of de novo transcription. Despite the collective understanding that RNAs are packaged into herpesvirus virions, many questions remain. This review will highlight what is known regarding packaged coding and non-coding RNAs and discuss their potential impact to virus biology.

Original languageEnglish (US)
Article numberArticle 81
JournalFrontiers in Genetics
Issue numberNOV
StatePublished - 2011
Externally publishedYes


  • Herpesvirus
  • Virion

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Genetics(clinical)


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