Abstract
The free radical production of cells exposed to polyglycolide (PLG) particles was measured to examine the oxidative burst occurring in cells after exposure to biodegradable poly(α-hydroxyl) acid surgical implants. It demonstrated that free radicals were only produced in response to protein-coated particles. The particle-bound proteins were present in a denatured form and it was in this conformation that elicits the foreign-body response. The oxidative burst in cells exposed to PLG particles occurs only when non-native proteins were bound to PLG.
Original language | English (US) |
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Number of pages | 1 |
State | Published - 1998 |
Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
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City | San Antonio, TX, USA |
Period | 2/6/98 → 2/8/98 |
ASJC Scopus subject areas
- Engineering(all)