Overview of Antifungal Agents

George R. Thompson; Jose Cadena; Thomas F. Patterson

doi:10.1016/j.ccm.2009.02.001

Overview of Antifungal Agents

George R. Thompson, Jose Cadena, Thomas F. Patterson

Research output: Contribution to journal › Review article › peer-review

96 Scopus citations

Abstract

This article is a comprehensive clinically focused review of currently available antifungals administered by way of the intravenous or inhalational route: amphotericin B and its lipid formulations, fluconazole, itraconazole, posaconazole, voriconazole, caspofungin, micafungin, anidulafungin, and flucytosine. Emphasis is placed on pharmacodynamics and kinetics, drug interactions, adverse events, and evidence for their use. Selected clinical trials demonstrating the efficacy of these agents are also reviewed.

Original language	English (US)
Pages (from-to)	203-215
Number of pages	13
Journal	Clinics in Chest Medicine
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.ccm.2009.02.001
State	Published - Jun 2009

Keywords

Amphotericin
Echinocandins
Flucytosine
Fungal infection
Invasive mycoses
Triazoles

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1016/j.ccm.2009.02.001

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title = "Overview of Antifungal Agents",

abstract = "This article is a comprehensive clinically focused review of currently available antifungals administered by way of the intravenous or inhalational route: amphotericin B and its lipid formulations, fluconazole, itraconazole, posaconazole, voriconazole, caspofungin, micafungin, anidulafungin, and flucytosine. Emphasis is placed on pharmacodynamics and kinetics, drug interactions, adverse events, and evidence for their use. Selected clinical trials demonstrating the efficacy of these agents are also reviewed.",

keywords = "Amphotericin, Echinocandins, Flucytosine, Fungal infection, Invasive mycoses, Triazoles",

author = "Thompson, {George R.} and Jose Cadena and Patterson, {Thomas F.}",

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AU - Cadena, Jose

AU - Patterson, Thomas F.

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AB - This article is a comprehensive clinically focused review of currently available antifungals administered by way of the intravenous or inhalational route: amphotericin B and its lipid formulations, fluconazole, itraconazole, posaconazole, voriconazole, caspofungin, micafungin, anidulafungin, and flucytosine. Emphasis is placed on pharmacodynamics and kinetics, drug interactions, adverse events, and evidence for their use. Selected clinical trials demonstrating the efficacy of these agents are also reviewed.

KW - Amphotericin

KW - Echinocandins

KW - Flucytosine

KW - Fungal infection

KW - Invasive mycoses

KW - Triazoles

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JO - Clinics in Chest Medicine

JF - Clinics in Chest Medicine

IS - 2

ER -

Overview of Antifungal Agents

Abstract

Keywords

ASJC Scopus subject areas

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