Outcome of transfusion of K: 11 erythrocytes in a patient with anti-K11 antibody

Carolyn M. Kelley, Mark W. Karwal, Annette J. Schlueter, John D Olson

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background and objectives: The clinical significance of anti-K11 in red cell transfusion therapy is unknown. We report the outcome of transfusion of K:11 erythrocytes into a patient with a known anti-K11 antibody. Materials and methods: The patient was monitored clinically following transfusion of 11 units of K:11 erythrocytes. A red cell survival study with K:11 erythrocytes and a monocyte monolayer assay (MMA) were performed. Results: No adverse clinical outcome was detected. The red cell survival study showed normal survival of K:11 erythrocytes, and the MMA showed no increase in reactive monocytes. Conclusion: These findings suggest that K:11 red cells can safely be transfused to individuals with anti-K11 antibody.

Original languageEnglish (US)
Pages (from-to)205-208
Number of pages4
JournalVox Sanguinis
Volume74
Issue number3
DOIs
StatePublished - 1998
Externally publishedYes

Fingerprint

Anti-Idiotypic Antibodies
Erythrocytes
Monocytes
Cell Survival
Cell- and Tissue-Based Therapy
Survival

ASJC Scopus subject areas

  • Hematology

Cite this

Kelley, C. M., Karwal, M. W., Schlueter, A. J., & Olson, J. D. (1998). Outcome of transfusion of K: 11 erythrocytes in a patient with anti-K11 antibody. Vox Sanguinis, 74(3), 205-208. https://doi.org/10.1159/000030933

Outcome of transfusion of K : 11 erythrocytes in a patient with anti-K11 antibody. / Kelley, Carolyn M.; Karwal, Mark W.; Schlueter, Annette J.; Olson, John D.

In: Vox Sanguinis, Vol. 74, No. 3, 1998, p. 205-208.

Research output: Contribution to journalArticle

Kelley, CM, Karwal, MW, Schlueter, AJ & Olson, JD 1998, 'Outcome of transfusion of K: 11 erythrocytes in a patient with anti-K11 antibody', Vox Sanguinis, vol. 74, no. 3, pp. 205-208. https://doi.org/10.1159/000030933
Kelley, Carolyn M. ; Karwal, Mark W. ; Schlueter, Annette J. ; Olson, John D. / Outcome of transfusion of K : 11 erythrocytes in a patient with anti-K11 antibody. In: Vox Sanguinis. 1998 ; Vol. 74, No. 3. pp. 205-208.
@article{d10fb3881887434885df6cf09119fa0c,
title = "Outcome of transfusion of K: 11 erythrocytes in a patient with anti-K11 antibody",
abstract = "Background and objectives: The clinical significance of anti-K11 in red cell transfusion therapy is unknown. We report the outcome of transfusion of K:11 erythrocytes into a patient with a known anti-K11 antibody. Materials and methods: The patient was monitored clinically following transfusion of 11 units of K:11 erythrocytes. A red cell survival study with K:11 erythrocytes and a monocyte monolayer assay (MMA) were performed. Results: No adverse clinical outcome was detected. The red cell survival study showed normal survival of K:11 erythrocytes, and the MMA showed no increase in reactive monocytes. Conclusion: These findings suggest that K:11 red cells can safely be transfused to individuals with anti-K11 antibody.",
author = "Kelley, {Carolyn M.} and Karwal, {Mark W.} and Schlueter, {Annette J.} and Olson, {John D}",
year = "1998",
doi = "10.1159/000030933",
language = "English (US)",
volume = "74",
pages = "205--208",
journal = "Vox Sanguinis",
issn = "0042-9007",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Outcome of transfusion of K

T2 - 11 erythrocytes in a patient with anti-K11 antibody

AU - Kelley, Carolyn M.

AU - Karwal, Mark W.

AU - Schlueter, Annette J.

AU - Olson, John D

PY - 1998

Y1 - 1998

N2 - Background and objectives: The clinical significance of anti-K11 in red cell transfusion therapy is unknown. We report the outcome of transfusion of K:11 erythrocytes into a patient with a known anti-K11 antibody. Materials and methods: The patient was monitored clinically following transfusion of 11 units of K:11 erythrocytes. A red cell survival study with K:11 erythrocytes and a monocyte monolayer assay (MMA) were performed. Results: No adverse clinical outcome was detected. The red cell survival study showed normal survival of K:11 erythrocytes, and the MMA showed no increase in reactive monocytes. Conclusion: These findings suggest that K:11 red cells can safely be transfused to individuals with anti-K11 antibody.

AB - Background and objectives: The clinical significance of anti-K11 in red cell transfusion therapy is unknown. We report the outcome of transfusion of K:11 erythrocytes into a patient with a known anti-K11 antibody. Materials and methods: The patient was monitored clinically following transfusion of 11 units of K:11 erythrocytes. A red cell survival study with K:11 erythrocytes and a monocyte monolayer assay (MMA) were performed. Results: No adverse clinical outcome was detected. The red cell survival study showed normal survival of K:11 erythrocytes, and the MMA showed no increase in reactive monocytes. Conclusion: These findings suggest that K:11 red cells can safely be transfused to individuals with anti-K11 antibody.

UR - http://www.scopus.com/inward/record.url?scp=0031972090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031972090&partnerID=8YFLogxK

U2 - 10.1159/000030933

DO - 10.1159/000030933

M3 - Article

C2 - 9595651

AN - SCOPUS:0031972090

VL - 74

SP - 205

EP - 208

JO - Vox Sanguinis

JF - Vox Sanguinis

SN - 0042-9007

IS - 3

ER -