Outcome of sutured scleral fixated intraocular lens in Marfan syndrome in pediatric eyes

Parveen Sen, Yamini Attiku, Pramod Bhende, Ekta Rishi, Dhanashree Ratra, Kummamuri Sreelakshmi

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Purpose: To report the clinical outcomes and complications in eyes with Marfan syndrome with subluxated/dislocated lens undergoing sutured scleral fixated intraocular lens (SSFIOL) implantation. Methods: A retrospective review was done for a consecutive series of 73 eyes of 43 patients with Marfan syndrome, with age less than 18 years who underwent SSFIOL from July 2000 to June 2017. Postoperative best corrected visual acuity, intraocular pressure and refractive error, intraoperative and postoperative complications and time for the development of these complications were analyzed. Results: Visual acuity improved significantly to 0.43 ± 0.30 (p = 0.01), 0.40 ± 0.3 (p = 0.00) and 0.39 ± 0.3 (p = 0.00) logMAR units at 6 weeks, 1 year and at last follow-up, respectively. The refractive error reduced significantly (p = 0.056, 0.039 and 0.031) at 6 weeks, 1 year and final follow-up following surgery. Intraoperative complications included iatrogenic retinal break (n = 3) and surgical trauma to the iris (n = 1). Postoperative complications included increased intraocular pressure in 3 eyes (4.1%), intraocular lens dislocation/subluxation in 5 eyes (6.8%), retinal detachment in 3 eyes (4.1%), choroidal detachment in 1 eye (1.3%), pupillary capture in 15 eyes (20.5%), vitreous hemorrhage in 1 eye (1.3%), pre-retinal hemorrhage in 1 eye (1.3%) and hyphema in 1 eye (1.3%). Conclusion: SSFIOL provides good visual outcomes in eyes with ectopia lentis associated with Marfan syndrome. Complications can be seen in some cases, and the parents need to be counseled regarding the same before surgical intervention.

Original languageEnglish (US)
Pages (from-to)1531-1538
Number of pages8
JournalInternational Ophthalmology
Issue number6
StatePublished - Jun 1 2020
Externally publishedYes


  • Aphakia
  • Dislocated lens
  • Intraocular lens
  • Marfan syndrome
  • Scleral fixation
  • Subluxated lens

ASJC Scopus subject areas

  • Ophthalmology


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