Abstract
This chapter reviews issues which result from consideration of the optimal outcome measures. By its nature, the process of measurement requires reducing a dynamic process (the patient dealing with their disability) to a 2-dimensional snapshot (the patient's score at one point in time) that will be used to reflect a patient's condition. Measurement is usually an imperfect process, especially when relatively small treatment effects are expected. Multiple examples of available treatment instruments will be reviewed with an emphasis on their benefits and limitations for future use.
Original language | English (US) |
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Title of host publication | Neuromuscular Disorders in Clinical Practice |
Publisher | Springer New York |
Pages | 287-326 |
Number of pages | 40 |
Volume | 9781461465676 |
ISBN (Print) | 9781461465676, 1461465664, 9781461465669 |
DOIs | |
State | Published - Nov 1 2014 |
Externally published | Yes |
Keywords
- clinical trials
- outcome measures
- quality of life
- sensitivity
- specificity
ASJC Scopus subject areas
- Medicine(all)