Osteolytic calvarial lesions as initial presentation of latent neurosyphilis

Colin Son, Derek Samples, Andrew Brenner, John Floyd

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


We report a patient with human immunodeficiency virus infection whose initial presentation of neurosyphilis was painful calvarial lesions. A literature search reveals seven previous cases of calvarial involvement in early acquired syphilis but none in patients diagnosed with neurosyphilis. This patient emphasizes the need to consider atypical infections when encountering skull lesions, especially in the setting of human immunodeficiency virus co-infection.

Original languageEnglish (US)
Pages (from-to)909-910
Number of pages2
JournalJournal of Clinical Neuroscience
Issue number5
StatePublished - May 1 2015


  • Human immunodeficiency virus
  • Skull tumor
  • Syphilis
  • Syphilitic osteitis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)
  • Surgery


Dive into the research topics of 'Osteolytic calvarial lesions as initial presentation of latent neurosyphilis'. Together they form a unique fingerprint.

Cite this