Abstract
There are many pathologic conditions in the oral cavity in which there is an interaction between immune cells and bone. Several of these are of systemic origin such as Paget's disease, and other lytic or sclerosing lesions that can be found in the jaws. The two most common osseous lesions in the oral cavity are from periodontitis and endodontic lesions. Both are initiated by bacteria and cause bone loss due to a host response to bacteria. Another cause of accelerated bone remodeling is due to orthodontic tooth movement. The movement of teeth through bone is due to the impact of cells, in the periodontal ligament and is thought to involve leukocytes associated with a sterile host response to mechanical forces.
| Original language | English (US) |
|---|---|
| Title of host publication | Osteoimmunology: Interactions of the Immune and Skeletal Systems: Second Edition |
| Publisher | Elsevier Inc. |
| Pages | 325-344 |
| Number of pages | 20 |
| ISBN (Print) | 9780128005712 |
| DOIs | |
| State | Published - Oct 6 2015 |
| Externally published | Yes |
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Keywords
- Bone formation
- Chemokines
- Cytokines
- Endodontic
- Gingivitis
- Immune response
- Lesions
- Orthodontic
- Periodontal
ASJC Scopus subject areas
- Medicine(all)
- Immunology and Microbiology(all)
Cite this
Osteoimmunology in the Oral Cavity (Periodontal Disease, Lesions of Endodontic Origin, and Orthodontic Tooth Movement). / Graves, Dana T.; Kayal, Rayyan A.; Oates, Thomas; Garlet, Gustavo P.
Osteoimmunology: Interactions of the Immune and Skeletal Systems: Second Edition. Elsevier Inc., 2015. p. 325-344.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Osteoimmunology in the Oral Cavity (Periodontal Disease, Lesions of Endodontic Origin, and Orthodontic Tooth Movement)
AU - Graves, Dana T.
AU - Kayal, Rayyan A.
AU - Oates, Thomas
AU - Garlet, Gustavo P.
PY - 2015/10/6
Y1 - 2015/10/6
N2 - There are many pathologic conditions in the oral cavity in which there is an interaction between immune cells and bone. Several of these are of systemic origin such as Paget's disease, and other lytic or sclerosing lesions that can be found in the jaws. The two most common osseous lesions in the oral cavity are from periodontitis and endodontic lesions. Both are initiated by bacteria and cause bone loss due to a host response to bacteria. Another cause of accelerated bone remodeling is due to orthodontic tooth movement. The movement of teeth through bone is due to the impact of cells, in the periodontal ligament and is thought to involve leukocytes associated with a sterile host response to mechanical forces.
AB - There are many pathologic conditions in the oral cavity in which there is an interaction between immune cells and bone. Several of these are of systemic origin such as Paget's disease, and other lytic or sclerosing lesions that can be found in the jaws. The two most common osseous lesions in the oral cavity are from periodontitis and endodontic lesions. Both are initiated by bacteria and cause bone loss due to a host response to bacteria. Another cause of accelerated bone remodeling is due to orthodontic tooth movement. The movement of teeth through bone is due to the impact of cells, in the periodontal ligament and is thought to involve leukocytes associated with a sterile host response to mechanical forces.
KW - Bone formation
KW - Chemokines
KW - Cytokines
KW - Endodontic
KW - Gingivitis
KW - Immune response
KW - Lesions
KW - Orthodontic
KW - Periodontal
UR - http://www.scopus.com/inward/record.url?scp=84966989684&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84966989684&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-800571-2.00019-0
DO - 10.1016/B978-0-12-800571-2.00019-0
M3 - Chapter
AN - SCOPUS:84966989684
SN - 9780128005712
SP - 325
EP - 344
BT - Osteoimmunology: Interactions of the Immune and Skeletal Systems: Second Edition
PB - Elsevier Inc.
ER -