Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing ctx-m extended-spectrum β-lactamases

Vidhya Prakash, James S. Lewis, Monica L. Herrera, Brian L. Wickes, James H. Jorgensen

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Effective therapeutic options are needed for community-onset urinary tract infections due to Escherichia coli strains that produce CTX-M extended-spectrum β-lactamases. We examined 46 urinary isolates producing CTX-M against several oral or long-acting parenteral antimicrobial agents. Approximately 90% were susceptible to fosfomycin and to a combination of cefdinir plus amoxicillin-clavulanate. All were susceptible to ertapenem.

Original languageEnglish (US)
Pages (from-to)1278-1280
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume53
Issue number3
DOIs
StatePublished - Mar 2009

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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