Oral and Oropharyngeal Cancer

Michaell A. Huber, Bundhit Tantiwongkosi

Research output: Contribution to journalReview articlepeer-review

65 Scopus citations


Oral and oropharyngeal cancer (OPC) is a complex and often relentless malignancy prone to local invasion and dissemination. Despite advances in understanding of the disease and improved therapeutic interventions, it continues to be diagnosed at an advanced stage and the survival rate remains poor. The financial cost of treating OPC may be the highest of all cancers in the United States and survivors often experience major detriments to quality of life. Major risk factors for OPC are tobacco, alcohol, areca nut, and human papillomavirus infection. This article updates medical practitioners on the causes, presentation, diagnosis, and management of OPC.

Original languageEnglish (US)
Pages (from-to)1299-1321
Number of pages23
JournalMedical Clinics of North America
Issue number6
StatePublished - Nov 1 2014


  • Alcohol
  • Areca nut
  • Biopsy
  • HPV
  • Oral cavity
  • Oropharynx
  • Squamous cell carcinoma
  • Tobacco

ASJC Scopus subject areas

  • General Medicine


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