Optoacoustic imaging: Application to the detection of foreign bodies

Leland Page, Saher Maswadi, Randolph D. Glickman, Norman Barsalou, Ron Branstetter, Scott Thompson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations


Detection of non-radio-opaque foreign bodies can be difficult. Current imaging modalities employed for detection of foreign bodies include: X-ray computed tomography, magnetic resonance, and ultrasound. Successful diagnosis of the presence of foreign bodies is variable because of the difficulty of differentiating them from soft tissue, gas, and bone. We are applying laser-induced optoacoustic imaging to the detection of foreign bodies. Tissue-simulating phantoms containing various common foreign bodies have been constructed. Images of these phantoms were generated by two laser-based optoacoustic methods utilizing different detection modalities. A pre-commercial imager developed by Seno Medical Instruments (San Antonio), incorporated an ultrasound transducer to detect induced optoacoustic responses, while a laboratory-built imaging system utilized an optical probe beam deflection technique (PBDT) to detect the optoacoustic responses. The laboratory-built unit also included an optical parametric oscillator as the pump, providing tunable wavelength output to optimize the optoacoustic measurements by probing the foreign bodies at their maximum optical absorption. Results to date have been encouraging; both methodologies have allowed us to reconstruct successfully the image of foreign-body containing phantoms. In preliminary work the PBDT approach appeared to produce higher resolution than did the ultrasound detector, possibly because PBDT is not constrained by the lower bandwidth limit imposed on the ultrasound transducer necessary to increase imaging depth. During the research in progress, we will compare the optoacoustic images to those generated by MRI, CT, and ultrasound, and continue to improve the resolution of the technique by using multiple detection sensors, and to improve image contrast by scanning foreign bodies over a range of wavelengths.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
StatePublished - 2009
EventPhotons Plus Ultrasound: Imaging and Sensing 2009 - San Jose, CA, United States
Duration: Jan 25 2009Jan 28 2009


OtherPhotons Plus Ultrasound: Imaging and Sensing 2009
Country/TerritoryUnited States
CitySan Jose, CA


  • Foreign bodies
  • Laser
  • Optoacoustic

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics


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