Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study

Jason Zalev, Bryan Clingman, Don Herzog, Tom Miller, Michael Ulissey, A. T. Stavros, Alexander Oraevsky, Philip Lavin, Kenneth Kist, N. C. Dornbluth, Pamela Otto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Abstract

Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic ultrasound (CDU). The Feasibility Study included OA imagery of 74 breast masses that were collected using the investigational Imagio® breast imaging system. Superior specificity and equal sensitivity to CDU was demonstrated, suggesting that OA fusion imaging may potentially obviate the need for negative biopsies without missing cancers in a certain percentage of breast masses. Preliminary results from a 100 subject Pilot Study are also discussed. A larger Pivotal Study (n=2,097 subjects) is underway to confirm the Feasibility Study and Pilot Study findings.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume9419
ISBN (Print)9781628415094
DOIs
StatePublished - 2015
EventMedical Imaging 2015: Ultrasonic Imaging and Tomography - Orlando, United States
Duration: Feb 22 2015Feb 23 2015

Other

OtherMedical Imaging 2015: Ultrasonic Imaging and Tomography
CountryUnited States
CityOrlando
Period2/22/152/23/15

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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    Zalev, J., Clingman, B., Herzog, D., Miller, T., Ulissey, M., Stavros, A. T., Oraevsky, A., Lavin, P., Kist, K., Dornbluth, N. C., & Otto, P. (2015). Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 9419). [941909] SPIE. https://doi.org/10.1117/12.2081679