Ontology-based knowledge acquisition for neuromotor functional recovery in stroke

Christopher Townsend, Jingshan Huang, Dejing Dou, Haishan Liu, Lei He, Patrick Hayes, Robert Rudnick, Hardik Shah, Dennis Fell, Wei Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Hemiparesis is the most common impairment after stroke, the leading cause of adult disability in the United States. The initial severity of hemiparesis had been the strongest predictor of neuromotor functional recovery level. However, the intervention response of stroke survivors does not always correlate with their initial level of impairment. This implies the existence of other factors that may significantly affect stroke survivors' recovery process. In order to design targeting intervention therapy strategies, it is critical to consider these factors in a principled, comprehensive way so that physical rehabilitation (PR) researchers may predict which stroke survivors will respond best to therapy and subsequently, determine if a particular type of therapy is a more optimal match. Currently, such prediction is primarily a manual process and remains a challenging task to PR researchers and clinicians. We propose a computing framework based upon a domain-specific ontology. This framework aims to facilitate knowledge acquisition from existing sources via semantics-enhanced data mining (SEDM) techniques. As a result, it will assist PR researchers and clinicians in better predicting stroke survivors' neuromotor functional recovery level, and will help physical therapists customize most etTective intervention therapy plans for individual stroke survivors.

Original languageEnglish (US)
Title of host publication2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010
Pages424-429
Number of pages6
DOIs
StatePublished - 2010
Externally publishedYes
Event2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010 - HongKong, China
Duration: Dec 18 2010Dec 21 2010

Publication series

Name2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010

Other

Other2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010
Country/TerritoryChina
CityHongKong
Period12/18/1012/21/10

Keywords

  • Data mining
  • Extremity dysfunction
  • Formal semantics
  • Hemiparesis
  • Intervention therapy
  • Neuromotor functional recovery
  • Ontology
  • Stroke

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics

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