Ontogeny of hematological cell and biochemical profiles in maternal and fetal baboons (Papio species)

Natalia E. Schlabritz-Loutsevitch, Gene B. Hubbard, Susan L. Jenkins, Helen C. Martin, Cathy S. Snider, Patrice A. Frost, M. Michelle Leland, Lorena M. Havill, Thomas J. McDonald, Peter W. Nathanielsz

    Research output: Contribution to journalArticle

    10 Scopus citations

    Abstract

    The normal ranges of hematological cell profiles and biochemistry are documented in adult non-pregnant, pregnant, juvenile, and neonatal baboons. Despite the extensive use of the baboon as a model for the study of various aspects of pregnancy, there is no data from paired mothers and their fetuses at different stages of gestation. Hematologic and biochemical profile data were obtained from eight non-pregnant female baboons, 37 mothers and 38 fetal baboons at 30 ± 2, 90 ± 2, 125 ± 2, and 175 ± 2 days of gestation (mean ± range; dGA; term, 180 dGA). Changes observed in fetal and maternal blood during normal baboon pregnancy were similar to those reported in human pregnancy. The level of alkaline phosphatase was two times higher in fetal blood circulation than that reported in human pregnancy.

    Original languageEnglish (US)
    Pages (from-to)193-200
    Number of pages8
    JournalJournal of medical primatology
    Volume34
    Issue number4
    DOIs
    StatePublished - Aug 1 2005

    Keywords

    • Blood biochemistry
    • Blood hematology
    • Nonhuman primates
    • Pregnancy

    ASJC Scopus subject areas

    • Animal Science and Zoology
    • veterinary(all)

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