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Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

  • Min Ju Park
  • , Hailian Shen
  • , Jason M. Spaeth
  • , Jaana H. Tolvanen
  • , Courtney Failor
  • , Jennifer F. Knudtson
  • , Jessica McLaughlin
  • , Sunil K. Halder
  • , Qiwei Yang
  • , Serdar E. Bulun
  • , Ayman Al-Hendy
  • , Robert S. Schenken
  • , Lauri A. Aaltonen
  • , Thomas G. Boyer

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