On ‘Deuterium exchange of poly-dl-alanine in aqueous solution’ by Arieh Berger and K. Linderstrøm-Lang

Andrew P. Hinck

Research output: Contribution to journalComment/debatepeer-review

Abstract

This commentary highlights the landmark manuscript published in 1957 by Arieh Berger and K. Linderstrøm-Lang that describes the measurement and analysis of hydrogen exchange rates. This highly referenced manuscript is recognized because the impact hydrogen exchange has had on characterizing the structure and dynamics of natively folded proteins and folding intermediates.

Original languageEnglish (US)
Article number109185
JournalArchives of Biochemistry and Biophysics
Volume726
DOIs
StatePublished - Sep 15 2022
Externally publishedYes

Keywords

  • HDX-MS
  • Hydrogen exchange
  • NMR
  • Protein dynamics
  • Protein stability

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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