On-chip detection of clinical Ebola virus RNA using specific DNA binding technique

H. Cai, J. W. Parks, R. Carrion, L. Zempoaltecatl, J. L. Patterson, A. R. Hawkins, H. Schmidt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Clinical Ebola RNAs are detected with virus concentration down to 6.25 ×104 pfu/ml on an optofluidic chip. Longer complementary pull-down DNA sequences provide better isolation and higher signals.

Original languageEnglish (US)
Title of host publicationCLEO
Subtitle of host publicationApplications and Technology, CLEO_AT 2014
PublisherOptical Society of America (OSA)
ISBN (Print)9781557529992
StatePublished - Jan 1 2014
Externally publishedYes
EventCLEO: Applications and Technology, CLEO_AT 2014 - San Jose, CA, United States
Duration: Jun 8 2014Jun 13 2014

Other

OtherCLEO: Applications and Technology, CLEO_AT 2014
CountryUnited States
CitySan Jose, CA
Period6/8/146/13/14

Fingerprint

DNA sequences
viruses
RNA
Viruses
isolation
DNA
deoxyribonucleic acid
chips

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Cai, H., Parks, J. W., Carrion, R., Zempoaltecatl, L., Patterson, J. L., Hawkins, A. R., & Schmidt, H. (2014). On-chip detection of clinical Ebola virus RNA using specific DNA binding technique. In CLEO: Applications and Technology, CLEO_AT 2014 Optical Society of America (OSA).

On-chip detection of clinical Ebola virus RNA using specific DNA binding technique. / Cai, H.; Parks, J. W.; Carrion, R.; Zempoaltecatl, L.; Patterson, J. L.; Hawkins, A. R.; Schmidt, H.

CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of America (OSA), 2014.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cai, H, Parks, JW, Carrion, R, Zempoaltecatl, L, Patterson, JL, Hawkins, AR & Schmidt, H 2014, On-chip detection of clinical Ebola virus RNA using specific DNA binding technique. in CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of America (OSA), CLEO: Applications and Technology, CLEO_AT 2014, San Jose, CA, United States, 6/8/14.
Cai H, Parks JW, Carrion R, Zempoaltecatl L, Patterson JL, Hawkins AR et al. On-chip detection of clinical Ebola virus RNA using specific DNA binding technique. In CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of America (OSA). 2014
Cai, H. ; Parks, J. W. ; Carrion, R. ; Zempoaltecatl, L. ; Patterson, J. L. ; Hawkins, A. R. ; Schmidt, H. / On-chip detection of clinical Ebola virus RNA using specific DNA binding technique. CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of America (OSA), 2014.
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