OMGProm: A database of orthologous mammalian gene promoters

Saranyan K. Palaniswamy, Victor X. Jin, Han Sun, Ramana V. Davuluri

Research output: Contribution to journalComment/debatepeer-review

17 Scopus citations

Abstract

Summary: Sequence comparisons between human and rodents are increasingly being used for the identification of gene regulatory regions. The effectiveness of such an approach largely depends on the quality and availability of promoter sequences. We developed OMG-Prom by integrating three data sources: (1) experimentally supported full-length cDNA, promoter and first exon sequences; (2) homology information from HomoloGene and (3) the human and mouse genomic sequences. The current version of OMGProm contains 8550 promoter pairs of 6373 orthologous human and mouse genes, where supporting experimental evidence for transcription start site annotation exists in at least one species.

Original languageEnglish (US)
Pages (from-to)835-836
Number of pages2
JournalBioinformatics
Volume21
Issue number6
DOIs
StatePublished - Mar 15 2005

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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