Of mice and women: do sex-dependent responses to ischemia-reperfusion injury in rodents have implications for delayed graft function in humans?

Christina M. Wyatt; P. Toby Coates; W. Brian Reeves

doi:10.1016/j.kint.2016.05.008

Of mice and women: do sex-dependent responses to ischemia-reperfusion injury in rodents have implications for delayed graft function in humans?

Christina M. Wyatt, P. Toby Coates, W. Brian Reeves

Department of Medicine

Research output: Contribution to journal › Comment/debate › peer-review

4 Scopus citations

Abstract

In rodent models, female sex has been shown to be protective against ischemia-reperfusion injury. A recent publication suggests that this sex-dependent response to injury may have clinical implications for delayed graft function after kidney transplantation.

Original language	English (US)
Pages (from-to)	10-13
Number of pages	4
Journal	Kidney international
Volume	90
Issue number	1
DOIs	https://doi.org/10.1016/j.kint.2016.05.008
State	Published - Jul 1 2016

ASJC Scopus subject areas

Nephrology

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10.1016/j.kint.2016.05.008

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title = "Of mice and women: do sex-dependent responses to ischemia-reperfusion injury in rodents have implications for delayed graft function in humans?",

abstract = "In rodent models, female sex has been shown to be protective against ischemia-reperfusion injury. A recent publication suggests that this sex-dependent response to injury may have clinical implications for delayed graft function after kidney transplantation.",

author = "Wyatt, {Christina M.} and Coates, {P. Toby} and Reeves, {W. Brian}",

note = "Publisher Copyright: {\textcopyright} 2016 International Society of Nephrology",

year = "2016",

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AU - Wyatt, Christina M.

AU - Coates, P. Toby

AU - Reeves, W. Brian

PY - 2016/7/1

Y1 - 2016/7/1

N2 - In rodent models, female sex has been shown to be protective against ischemia-reperfusion injury. A recent publication suggests that this sex-dependent response to injury may have clinical implications for delayed graft function after kidney transplantation.

AB - In rodent models, female sex has been shown to be protective against ischemia-reperfusion injury. A recent publication suggests that this sex-dependent response to injury may have clinical implications for delayed graft function after kidney transplantation.

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Of mice and women: do sex-dependent responses to ischemia-reperfusion injury in rodents have implications for delayed graft function in humans?

Abstract

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