Ocular flutter following Zika virus infection

Emely Karam, Jose Giraldo, Flor Rodriguez, Carlos E. Hernandez-Pereira, Alfonso J. Rodriguez-Morales, Gabriela M. Blohm, Alberto E. Paniz-Mondolfi

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Zika virus (ZIKV) is an emerging flavivirus which has been linked to a number of neurologic manifestations such as Guillain-Barré syndrome (GBS), transverse myelitis, and meningo-encephalitis. Ophthalmologic manifestations are increasingly being reported; however, ocular dyskinesias have not been described in this context to date. Herein, we report a case of a 22-year-old female who presented with ocular flutter and associated Guillain-Barré syndrome following acute ZIKV infection. We speculate that although such symptoms may have originated from a direct viral insult, a post-infectious autoimmune mechanism may not be excluded. Physicians should include ZIKV as well as other flaviviruses in their diagnostic workup for all patients with ocular flutter/opsoclonus, after excluding other non-infectious causes of central nervous system pathology. To the best of our knowledge, this is the first report on the association of ocular flutter, GBS, and ZIKV infection.

Original languageEnglish (US)
Pages (from-to)932-934
Number of pages3
JournalJournal of NeuroVirology
Issue number6
StatePublished - Dec 1 2017
Externally publishedYes


  • Guillain-Barré syndrome
  • Ocular flutter
  • Viral
  • Zika virus

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Virology


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