Occurrence of circulating immune complexes in β-thalassaemia major

P. Casali, P. Borzini, D. Vergani, G. Mieli-Vergani, G. Masera, C. Zanussi

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The presence of circulating soluble immune complexes and the level of complement were investigated in sera from 21 patients with β thalassaemia major, including both splenectomised and nonsplenectomised patients. A high level of immune complexes was found in half of these cases. Reduced complement levels were seen less frequently. There was no correlation between the presence of circulating immune complexes, decreased complement levels, and the presence or absence of the spleen. The level of immune complexes increased with the age of the individual, i.e. with the duration of the disease.

Original languageEnglish (US)
Pages (from-to)141-143
Number of pages3
JournalUnknown Journal
Issue number2
StatePublished - 1978
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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