Abstract
Type II thyroxine 5′-deiodinase (5′-D) activity in both pineal and Harderian glands of the Swiss mouse was studied. Pineal 5′-D activity exhibited a nyctohemeral profile with a maximal peak value at 05.00 h, which coincides with that for pineal melatonin production. However, no rhythm of 5′-D activity in the Harderian gland could be found. In pineal gland, light at night inhibited the nocturnal increase in 5′-D activity, while isoproterenol, a β-adrenergic agonist, could not stimulate the enzyme. In the Harderian gland, neither darkness, nor light at night, or isoproterenol were capable of modifying basal values of 5′-D activity.
Original language | English (US) |
---|---|
Pages (from-to) | 111-117 |
Number of pages | 7 |
Journal | Bioscience Reports |
Volume | 11 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1991 |
Keywords
- Harderian
- Swiss mouse
- deiodinase
- pineal
- thyroxine
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology