Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

C. Osuna; A. Rubio; J. Jimenez; R. J. Reiter; J. M. Guerrero

Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

C. Osuna, A. Rubio, J. Jimenez, R. J. Reiter, J. M. Guerrero

Research output: Contribution to journal › Article › peer-review

Abstract

Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.

Original language	English (US)
Pages (from-to)	21-24
Number of pages	4
Journal	Annual Review of Chronopharmacology
Volume	7
State	Published - 1990
Externally published	Yes

ASJC Scopus subject areas

Pharmacology

Cite this

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title = "Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse",

abstract = "Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.",

author = "C. Osuna and A. Rubio and J. Jimenez and Reiter, \{R. J.\} and Guerrero, \{J. M.\}",

year = "1990",

language = "English (US)",

volume = "7",

pages = "21--24",

journal = "Annual Review of Chronopharmacology",

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T1 - Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

AU - Osuna, C.

AU - Rubio, A.

AU - Jimenez, J.

AU - Reiter, R. J.

AU - Guerrero, J. M.

PY - 1990

Y1 - 1990

N2 - Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.

AB - Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.

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SN - 0743-9539

VL - 7

SP - 21

EP - 24

JO - Annual Review of Chronopharmacology

JF - Annual Review of Chronopharmacology

ER -

Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

Abstract

ASJC Scopus subject areas

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