Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

C. Osuna; A. Rubio; J. Jimenez; R. J. Reiter; J. M. Guerrero

Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

C. Osuna, A. Rubio, J. Jimenez, R. J. Reiter, J. M. Guerrero

Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

Abstract

Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.

Original language	English (US)
Pages (from-to)	21-24
Number of pages	4
Journal	Annual Review of Chronopharmacology
Volume	7
State	Published - 1990

ASJC Scopus subject areas

Pharmacology

Access to Document

Fingerprint Dive into the research topics of 'Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse'. Together they form a unique fingerprint.

Cite this

@article{52ba3250f6004d2195c302c63ce939d1,

title = "Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse",

abstract = "Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.",

author = "C. Osuna and A. Rubio and J. Jimenez and Reiter, {R. J.} and Guerrero, {J. M.}",

year = "1990",

language = "English (US)",

volume = "7",

pages = "21--24",

journal = "Chronobiology International",

issn = "0742-0528",

publisher = "Informa Healthcare",

}

TY - JOUR

T1 - Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse

AU - Osuna, C.

AU - Rubio, A.

AU - Jimenez, J.

AU - Reiter, R. J.

AU - Guerrero, J. M.

PY - 1990

Y1 - 1990

N2 - Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.

AB - Type II thyroxine 5'-deiodinase activity in both pineal and Harderian glands of the swiss mouse were studied. We show that pineal 5'-deiodinase activity exhibits a nyctohemeral profile with a maximal peak value at 05.00 h coincident with that for pineal melatonin. However, no rhythm of 5'-deiodinase activity was found in the Harderian gland. These results suggest at least a common regulatory mechanism for type II thyroxine 5'-deiodinase and melatonin production, and probably, an interrelationship between these two metabolic pathways.

UR - http://www.scopus.com/inward/record.url?scp=0025044260&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025044260&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0025044260

VL - 7

SP - 21

EP - 24

JO - Chronobiology International

JF - Chronobiology International

SN - 0742-0528

ER -