TY - JOUR
T1 - Nutrition and vitamin deficiencies are common in orthopaedic trauma patients
AU - Handcox, Jordan E.
AU - Gutierrez‐naranjo, Jose M.
AU - Salazar, Luis M.
AU - Bullock, Travis S.
AU - Griffin, Leah P.
AU - Zelle, Boris A.
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - Macro‐ and micronutrients play important roles in the biological wound‐healing pathway. Although deficiencies may potentially affect orthopaedic trauma patient outcomes. Data on nutritional deficiencies in orthopaedic trauma patients remain limited in the literature. The purpose of this study was to (1) evaluate the prevalence of macro‐ and micronutrient deficiencies in orthopaedic trauma patients with lower extremity fractures and (2) evaluate the impact of such deficiencies on surgical site complications. This retrospective study identified 867 patients with lower extremity fractures treated with surgical fixation from 2019 to 2020. Data recorded included albumin, prealbu-min, protein, vitamins A/C/D, magnesium, phosphorus, transferrin and zinc, as well as wound com-plications. Nutritional deficiencies were found for prealbumin, albumin and transferrin at 50.5%, 23.4% and 48.5%, respectively. Furthermore, a high prevalence of micronutrient deficiencies (vita-min A, 35.4%; vitamin C, 54.4%; vitamin D, 75.4%; and zinc, 56.5%) was observed. We also recorded a statistically significant difference in wound complications in patients who were deficient in prealbumin (21.6% vs. 6.6%, p = 0.0142) and vitamin C (56.8% vs. 28.6%, p = 0.0236). Our study out-lines the prevalence of nutritional deficiencies in an orthopaedic trauma population and identifies areas for possible targeted supplementation to decrease wound complications.
AB - Macro‐ and micronutrients play important roles in the biological wound‐healing pathway. Although deficiencies may potentially affect orthopaedic trauma patient outcomes. Data on nutritional deficiencies in orthopaedic trauma patients remain limited in the literature. The purpose of this study was to (1) evaluate the prevalence of macro‐ and micronutrient deficiencies in orthopaedic trauma patients with lower extremity fractures and (2) evaluate the impact of such deficiencies on surgical site complications. This retrospective study identified 867 patients with lower extremity fractures treated with surgical fixation from 2019 to 2020. Data recorded included albumin, prealbu-min, protein, vitamins A/C/D, magnesium, phosphorus, transferrin and zinc, as well as wound com-plications. Nutritional deficiencies were found for prealbumin, albumin and transferrin at 50.5%, 23.4% and 48.5%, respectively. Furthermore, a high prevalence of micronutrient deficiencies (vita-min A, 35.4%; vitamin C, 54.4%; vitamin D, 75.4%; and zinc, 56.5%) was observed. We also recorded a statistically significant difference in wound complications in patients who were deficient in prealbumin (21.6% vs. 6.6%, p = 0.0142) and vitamin C (56.8% vs. 28.6%, p = 0.0236). Our study out-lines the prevalence of nutritional deficiencies in an orthopaedic trauma population and identifies areas for possible targeted supplementation to decrease wound complications.
KW - Lower extremity
KW - Nutrition wound healing
KW - Nutritional deficiencies
KW - Orthopaedic trauma
KW - Vitamins
KW - Wound compli-cations
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U2 - 10.3390/jcm10215012
DO - 10.3390/jcm10215012
M3 - Article
C2 - 34768533
AN - SCOPUS:85117964303
SN - 2077-0383
VL - 10
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 21
M1 - 5012
ER -