Numerical model study of dual frequency conductance measurement of left ventricular volume in the mouse

John A. Pearce, Marc D. Feldman

Research output: Contribution to journalConference article

2 Scopus citations

Abstract

Instantaneous measurement of ventricular volume using tetrapolar conductance catheters facilitates evaluation of the effects of genetic alterations and cardio-genic drugs on ventricular function with pressure-volume loop analysis. The parallel conductance of cardiac muscle causes errors in left ventricular volume estimation. The frequency dependence of the effective conductance of cardiac muscle can be used to correct the measured conductance signal to reflect only the conductance of blood. Finite difference method numerical models of the electric and current density fields have been used to study the relative contributions of blood and muscle to the measured conductance signal in the mouse left ventricle.

Original languageEnglish (US)
Pages (from-to)1260-1261
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
StatePublished - Dec 1 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Keywords

  • Conductance catheter
  • Numerical models
  • Ventricular volume

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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