Novel treatments for chronic hepatitis C: closing the remaining gaps

Naim Alkhouri, Eric Lawitz, Fred Poordad

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

Direct acting antivirals (DAAs) have revolutionized the treatment of chronic hepatitis C virus (HCV) infection with cure rates >90% for the majority of patients and excellent safety profile. However, there remain certain unmet needs in treating HCV including treatment for patients that failed a prior DAA regimen and for those with advanced chronic kidney disease. In addition, shortening the duration of DAA regimens has the potential to increase compliance and decrease the cost of care. New regimens that were approved by the FDA in 2017 address these unmet needs and will be discussed in this concise review.

Original languageEnglish (US)
Pages (from-to)107-111
Number of pages5
JournalCurrent Opinion in Pharmacology
Volume37
DOIs
StatePublished - Dec 2017

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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