Novel estrogen receptor coregulators and signaling molecules in human diseases

C. J. Barnes, R. K. Vadlamudi, R. Kumar

Research output: Contribution to journalReview article

39 Scopus citations

Abstract

The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.

Original languageEnglish (US)
Pages (from-to)281-291
Number of pages11
JournalCellular and Molecular Life Sciences
Volume61
Issue number3
DOIs
StatePublished - Feb 2004
Externally publishedYes

Keywords

  • Breast cancer
  • Chromatin remodeling
  • Coregulators
  • Estrogen receptor
  • Signaling pathways

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Cellular and Molecular Neuroscience
  • Cell Biology

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