Novel estrogen receptor coregulators and signaling molecules in human diseases

C. J. Barnes; R. K. Vadlamudi; R. Kumar

doi:10.1007/s00018-003-3222-5

Novel estrogen receptor coregulators and signaling molecules in human diseases

C. J. Barnes, R. K. Vadlamudi, R. Kumar

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.

Original language	English (US)
Pages (from-to)	281-291
Number of pages	11
Journal	Cellular and Molecular Life Sciences
Volume	61
Issue number	3
DOIs	https://doi.org/10.1007/s00018-003-3222-5
State	Published - Feb 2004
Externally published	Yes

Keywords

Breast cancer
Chromatin remodeling
Coregulators
Estrogen receptor
Signaling pathways

ASJC Scopus subject areas

Molecular Medicine
Molecular Biology
Pharmacology
Cellular and Molecular Neuroscience
Cell Biology

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10.1007/s00018-003-3222-5

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abstract = "The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.",

keywords = "Breast cancer, Chromatin remodeling, Coregulators, Estrogen receptor, Signaling pathways",

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AU - Vadlamudi, R. K.

AU - Kumar, R.

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AB - The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.

KW - Breast cancer

KW - Chromatin remodeling

KW - Coregulators

KW - Estrogen receptor

KW - Signaling pathways

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M3 - Review article

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Novel estrogen receptor coregulators and signaling molecules in human diseases

Abstract

Keywords

ASJC Scopus subject areas

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