Abstract
1. 1. An important component of endothermy in small mammals is achieved by the employment of nonshivering thermogenesis (NST). 2. 2. Nonshivering thermogenic abilities of two subterranean mammals, the Damara mole-rat (Cryptomys damarensis) and the naked mole-rat (Heterocephalus glaber), were assessed by administering noradrenaline (0.8 mg/kg) to anaesthetized animals. These two species show very different modes of thermoregulation in that the former regulates body temperature whereas in the latter species body temperature closely tracks ambient temperature. 3. 3. Both species showed the characteristic NST response by significantly increasing metabolic rate (C. damarensis), 194 ± 57%; H. glaber, 356 ± 199%) and body temperature (C. damarensis, 4.1 ± 0.5°C; H. glaber, 2.8 ± 0.9°C) with noradrenaline intervention. 4. 4. These animals can therefore employ endothermy. While the Damara mole-rat conforms to mammalian thermoregulatory dogma and is homeothermic, the naked mole-rat may by definition be an 'endothermic poikilotherm'.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 25-32 |
| Number of pages | 8 |
| Journal | Journal of Thermal Biology |
| Volume | 19 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1994 |
| Externally published | Yes |
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Keywords
- Cryptomys damarensis
- Damara mole-rat
- endothermy
- Heterocephalus glaber
- naked mole-rat
- nonshivering thermogenesis
- Noradrenaline
- poikilotherm
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Physiology
Cite this
Noradrenaline induces nonshivering thermogenesis in both the naked mole-rat (Heterocephalus glaber) and the Damara mole-rat (Cryptomys damarensis) despite very different modes of thermoregulation. / Hislop, Michael S.; Buffenstein, Rochelle.
In: Journal of Thermal Biology, Vol. 19, No. 1, 1994, p. 25-32.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Noradrenaline induces nonshivering thermogenesis in both the naked mole-rat (Heterocephalus glaber) and the Damara mole-rat (Cryptomys damarensis) despite very different modes of thermoregulation
AU - Hislop, Michael S.
AU - Buffenstein, Rochelle
PY - 1994
Y1 - 1994
N2 - 1. 1. An important component of endothermy in small mammals is achieved by the employment of nonshivering thermogenesis (NST). 2. 2. Nonshivering thermogenic abilities of two subterranean mammals, the Damara mole-rat (Cryptomys damarensis) and the naked mole-rat (Heterocephalus glaber), were assessed by administering noradrenaline (0.8 mg/kg) to anaesthetized animals. These two species show very different modes of thermoregulation in that the former regulates body temperature whereas in the latter species body temperature closely tracks ambient temperature. 3. 3. Both species showed the characteristic NST response by significantly increasing metabolic rate (C. damarensis), 194 ± 57%; H. glaber, 356 ± 199%) and body temperature (C. damarensis, 4.1 ± 0.5°C; H. glaber, 2.8 ± 0.9°C) with noradrenaline intervention. 4. 4. These animals can therefore employ endothermy. While the Damara mole-rat conforms to mammalian thermoregulatory dogma and is homeothermic, the naked mole-rat may by definition be an 'endothermic poikilotherm'.
AB - 1. 1. An important component of endothermy in small mammals is achieved by the employment of nonshivering thermogenesis (NST). 2. 2. Nonshivering thermogenic abilities of two subterranean mammals, the Damara mole-rat (Cryptomys damarensis) and the naked mole-rat (Heterocephalus glaber), were assessed by administering noradrenaline (0.8 mg/kg) to anaesthetized animals. These two species show very different modes of thermoregulation in that the former regulates body temperature whereas in the latter species body temperature closely tracks ambient temperature. 3. 3. Both species showed the characteristic NST response by significantly increasing metabolic rate (C. damarensis), 194 ± 57%; H. glaber, 356 ± 199%) and body temperature (C. damarensis, 4.1 ± 0.5°C; H. glaber, 2.8 ± 0.9°C) with noradrenaline intervention. 4. 4. These animals can therefore employ endothermy. While the Damara mole-rat conforms to mammalian thermoregulatory dogma and is homeothermic, the naked mole-rat may by definition be an 'endothermic poikilotherm'.
KW - Cryptomys damarensis
KW - Damara mole-rat
KW - endothermy
KW - Heterocephalus glaber
KW - naked mole-rat
KW - nonshivering thermogenesis
KW - Noradrenaline
KW - poikilotherm
UR - http://www.scopus.com/inward/record.url?scp=0028042188&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028042188&partnerID=8YFLogxK
U2 - 10.1016/0306-4565(94)90006-X
DO - 10.1016/0306-4565(94)90006-X
M3 - Article
AN - SCOPUS:0028042188
VL - 19
SP - 25
EP - 32
JO - Journal of Thermal Biology
JF - Journal of Thermal Biology
SN - 0306-4565
IS - 1
ER -