Nonneoplastic Diseases and Disorders of the Testis

J. B. Lin, D. Troyer

Research output: Chapter in Book/Report/Conference proceedingChapter


This article discusses commonly encountered nonneoplastic disorders of the testis, including inflammatory and developmental conditions. Cryptorchidism is a commonly encountered disorder that can result in infertiLity as well as maLignancies of the testis. We will discuss the most common sex-chromosomal disorder, Klinefelter syndrome, followed by nonneoplastic diseases such as orchitis, malakoplakia, testicular torsion and infarction, splenogonadal fusion, adrenal cortical rest, and varicocele. Developmental disorders such as testicular feminization/androgen insensitivity syndrome, gonadal dysgenesis, and hermaphroditism will also be discussed. Finally, we will go over some miscellaneous abnormaLities such as hydrocele, epididymitis, and spermatic granuloma of the epididymis.

Original languageEnglish (US)
Title of host publicationPathobiology of Human Disease
Subtitle of host publicationA Dynamic Encyclopedia of Disease Mechanisms
PublisherElsevier Inc.
Number of pages4
ISBN (Electronic)9780123864567
ISBN (Print)9780123864574
StatePublished - Jan 1 2014
Externally publishedYes


  • Adrenal cortical rest
  • Atrophy
  • Cryptorchidism
  • Disorder of sex development
  • Epididymis
  • Gonadal dysgenesis
  • Klinefelter syndrome
  • Miscellaneous abnormaLities
  • Nonneoplastic human testis diseases
  • Orchitis
  • Pseudohermaphroditism
  • Spermatic granuloma of the epididymis
  • Splenogonadal fusion
  • Testicular feminization/androgen insensitivity syndrome
  • Torsion
  • True hermaphroditism
  • Varicocele

ASJC Scopus subject areas

  • Medicine(all)


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