Noninvasive spectroscopic diagnosis of superficial ocular lesions and corneal infections

J. R. Mourant, I. J. Bigio, D. C. Gritz, R. D. Glickman, T. Johnson, T. Shimada, K. StoreyHeld

Research output: Contribution to journalConference articlepeer-review

Abstract

The potential of a rapid noninvasive diagnostic system to detect tissue abnormalities on the surface of the eye has been investigated. The optical scatter signal from lesions and normal areas on the conjunctival sclera of the human eye were measured in vivo. It is possible to distinguish nonpigmented pingueculas from other lesions. The ability of the system to detect malignancies could not be tested because none of the measured and biopsied lesions were malignant. Optical scatter and fluorescence spectra of bacterial and fungal suspensions, and corneal irritations were also collected. Both scattering and fluorescence show potential for diagnosing corneal infections.

Original languageEnglish (US)
Pages (from-to)275-284
Number of pages10
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume2135
DOIs
StatePublished - May 19 1994
EventAdvances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases 1994 - Los Angeles, United States
Duration: Jan 23 1994Jan 29 1994

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Noninvasive spectroscopic diagnosis of superficial ocular lesions and corneal infections'. Together they form a unique fingerprint.

Cite this