TY - JOUR
T1 - Non-stroke neurological syndromes associated with antiphospholipid antibodies
T2 - Evaluation of clinical and experimental studies
AU - Chapman, J.
AU - Rand, J. H.
AU - Brey, R. L.
AU - Levine, S. R.
AU - Blatt, I.
AU - Khamashta, M. A.
AU - Shoenfeld, Y.
PY - 2003
Y1 - 2003
N2 - Although many types of neurological disorders and events have been described in association with antiphospholipid antibodies (aPL) and the antiphospholipid syndrome (APS), only ischaemic stroke is reasonably well established and accepted as a diagnostic criterion for the syndrome. We propose to evaluate, classify and rank the association of other neurological manifestations as possible, probable, or definite according to the data available from clinical studies and animal models. By these criteria, none of the neurological disorders or events such as epilepsy, psychiatric disease, dementia, transverse myelitis, multiple sclerosis-like disease, chorea, migraine, Guillian-Barrè syndrome, and sensory-neural hearing loss, can be definitely associated with aPL or APS.
AB - Although many types of neurological disorders and events have been described in association with antiphospholipid antibodies (aPL) and the antiphospholipid syndrome (APS), only ischaemic stroke is reasonably well established and accepted as a diagnostic criterion for the syndrome. We propose to evaluate, classify and rank the association of other neurological manifestations as possible, probable, or definite according to the data available from clinical studies and animal models. By these criteria, none of the neurological disorders or events such as epilepsy, psychiatric disease, dementia, transverse myelitis, multiple sclerosis-like disease, chorea, migraine, Guillian-Barrè syndrome, and sensory-neural hearing loss, can be definitely associated with aPL or APS.
KW - Antiphospholipid antibodies
KW - Cerebrovascular disease
KW - Chorea
KW - Dementia
KW - Epilepsy
KW - Migraine
KW - Multiple sclerosis
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U2 - 10.1191/0961203303lu392oa
DO - 10.1191/0961203303lu392oa
M3 - Article
C2 - 12892390
AN - SCOPUS:0038038350
VL - 12
SP - 514
EP - 517
JO - Lupus
JF - Lupus
SN - 0961-2033
IS - 7
ER -