Non-invasive quantification of cerebral blood flow for rats by micropet imaging of o labelled water: the application of a cardiac time-activity curve for the tracer arterial input function

Seong Hwan Yee, Paul A. Jerabek, Peter T. Fox

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

In-vivo quantitative cerebral blood flow (CBF) measurement using positron emission tomography (PET) has typically employed invasive arterial blood sampling procedure to determine the arterial input function (AIF). The present study was performed to provide a non-invasive quantitative CBF measurement technique for rats using a dedicated animal PET.

Original languageEnglish (US)
Pages (from-to)903-911
Number of pages9
JournalNuclear Medicine Communications
Volume26
Issue number10
DOIs
StatePublished - Oct 2005

Keywords

  • Arterial input function
  • CBF
  • Cardiac time-activity curve
  • Cerebral blood flow
  • MicroPET
  • Non-invasive
  • PET
  • Rat

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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