Non-coding RNAs in endodontic disease

Johnah Galicia, Asma A. Khan

Research output: Contribution to journalReview articlepeer-review

Abstract

The immunocompetence and regeneration potential of the dental pulp and its surrounding apical tissues have been investigated extensively in the field of endodontics. While research on the role of non-coding RNAs in these tissues is still in its infancy, it is envisioned that improved understanding of the regulatory function of ncRNAs in pulpal and periapical immune response will help prevent or treat endodontic disease. Of particular importance is the role of these RNAs in regenerating the dentin-pulp complex. In this review, we highlight recent progress on the role of non-coding RNAs in the immune response to endodontic infection as well as the repair and regenerative response to injury.

Original languageEnglish (US)
JournalSeminars in Cell and Developmental Biology
DOIs
StateAccepted/In press - 2021

Keywords

  • Dental
  • Epigenetic
  • MicroRNA
  • Non-coding RNA
  • SiRNAs

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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