TY - JOUR
T1 - Non-antibiotic therapies for CAP
AU - Faverio, Paola
AU - Restrepo, Marcos I.
PY - 2014/3
Y1 - 2014/3
N2 - Several novel non-antibiotic therapies have been used in patients with pneumonia. Among many alternatives, anti-inflammatory and immunomodulatory agents such as corticosteroids, statins, nonsteroid anti-inflammatory medications, immunoglobulins and anticoagulants have been tested. Other agents, such as angiotensin-converting enzyme inhibitors and mucolytics, showed a potential beneficial effect on airways protection mechanisms and secretion clearance. The therapeutic effect of nonpharmacological strategies (i.e. chest physiotherapy) has also been considered. However, other than use of corticosteroids in certain populations, there is still a need for further research before these medications are recommended forclinicaluse.This chapter discusses the evidence regarding novel non-antibiotic therapies and the association with clinical outcomes in patients with pneumonia.
AB - Several novel non-antibiotic therapies have been used in patients with pneumonia. Among many alternatives, anti-inflammatory and immunomodulatory agents such as corticosteroids, statins, nonsteroid anti-inflammatory medications, immunoglobulins and anticoagulants have been tested. Other agents, such as angiotensin-converting enzyme inhibitors and mucolytics, showed a potential beneficial effect on airways protection mechanisms and secretion clearance. The therapeutic effect of nonpharmacological strategies (i.e. chest physiotherapy) has also been considered. However, other than use of corticosteroids in certain populations, there is still a need for further research before these medications are recommended forclinicaluse.This chapter discusses the evidence regarding novel non-antibiotic therapies and the association with clinical outcomes in patients with pneumonia.
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U2 - 10.1183/1025448x.10004513
DO - 10.1183/1025448x.10004513
M3 - Article
AN - SCOPUS:84905732748
SN - 1025-448X
VL - 63
SP - 219
EP - 233
JO - European Respiratory Monograph
JF - European Respiratory Monograph
ER -