Nitroalkane oxidase: Structure and mechanism

Paul F Fitzpatrick

doi:10.1016/j.abb.2017.05.012

Nitroalkane oxidase: Structure and mechanism

Paul F Fitzpatrick

Biochemistry & Structural Biology

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

The flavoprotein nitroalkane oxidase catalyzes the oxidation of neutral nitroalkanes to the corresponding aldehydes or ketones, releasing nitrite and transferring electrons to O₂ to form H₂O₂. A combination of solution and structural analyses have provided a detailed understanding of the mechanism of this enzyme.

Original language	English (US)
Journal	Archives of Biochemistry and Biophysics
DOIs	https://doi.org/10.1016/j.abb.2017.05.012
State	Accepted/In press - Apr 20 2017

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Keywords

Flavoprotein
Mechanism
Nitroalkane oxidase
Nitronate monooxygenase
Structure

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology

Cite this

Fitzpatrick, P. F. (Accepted/In press). Nitroalkane oxidase: Structure and mechanism. Archives of Biochemistry and Biophysics. https://doi.org/10.1016/j.abb.2017.05.012

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abstract = "The flavoprotein nitroalkane oxidase catalyzes the oxidation of neutral nitroalkanes to the corresponding aldehydes or ketones, releasing nitrite and transferring electrons to O2 to form H2O2. A combination of solution and structural analyses have provided a detailed understanding of the mechanism of this enzyme.",

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KW - Nitronate monooxygenase

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Access to Document

10.1016/j.abb.2017.05.012