Nitroalkane oxidase: Structure and mechanism

Paul F. Fitzpatrick

doi:10.1016/j.abb.2017.05.012

Nitroalkane oxidase: Structure and mechanism

Paul F. Fitzpatrick

Biochemistry & Structural Biology

Research output: Contribution to journal › Review article

8 Scopus citations

Abstract

The flavoprotein nitroalkane oxidase catalyzes the oxidation of neutral nitroalkanes to the corresponding aldehydes or ketones, releasing nitrite and transferring electrons to O₂ to form H₂O₂. A combination of solution and structural analyses have provided a detailed understanding of the mechanism of this enzyme.

Original language	English (US)
Pages (from-to)	41-46
Number of pages	6
Journal	Archives of Biochemistry and Biophysics
Volume	632
DOIs	https://doi.org/10.1016/j.abb.2017.05.012
State	Published - Oct 15 2017

Keywords

Flavoprotein
Mechanism
Nitroalkane oxidase
Nitronate monooxygenase
Structure

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology

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10.1016/j.abb.2017.05.012

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Fitzpatrick, P. F. (2017). Nitroalkane oxidase: Structure and mechanism. Archives of Biochemistry and Biophysics, 632, 41-46. https://doi.org/10.1016/j.abb.2017.05.012

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abstract = "The flavoprotein nitroalkane oxidase catalyzes the oxidation of neutral nitroalkanes to the corresponding aldehydes or ketones, releasing nitrite and transferring electrons to O2 to form H2O2. A combination of solution and structural analyses have provided a detailed understanding of the mechanism of this enzyme.",

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AB - The flavoprotein nitroalkane oxidase catalyzes the oxidation of neutral nitroalkanes to the corresponding aldehydes or ketones, releasing nitrite and transferring electrons to O2 to form H2O2. A combination of solution and structural analyses have provided a detailed understanding of the mechanism of this enzyme.

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KW - Nitronate monooxygenase

KW - Structure

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