Nitroalkane oxidase: Structure and mechanism

Paul F. Fitzpatrick

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


The flavoprotein nitroalkane oxidase catalyzes the oxidation of neutral nitroalkanes to the corresponding aldehydes or ketones, releasing nitrite and transferring electrons to O2 to form H2O2. A combination of solution and structural analyses have provided a detailed understanding of the mechanism of this enzyme.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalArchives of Biochemistry and Biophysics
StatePublished - Oct 15 2017


  • Flavoprotein
  • Mechanism
  • Nitroalkane oxidase
  • Nitronate monooxygenase
  • Structure

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology


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