New strategies for treating AIDS

Paul A. Sandstrom, Thomas M. Folks

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    3 Scopus citations

    Abstract

    To date, the effective management of HIV-1 infection by anti-retroviral drugs has proved remarkably difficult to achieve. This is primarily due to the ease with which HIV-1 becomes resistant to drugs which initially may be very effective at blocking viral replication. In a recent issue of Science, two promising new AIDS treatments were reported. The first described the use of retroviral-type zinc finger structures found in the HIV-1 nucleocapsid protein as targets for antiretroviral drugs(1). The second demonstrated the feasibility of the reverse transcriptase inhibitor (R)-9-(2-phosphonylmethoxypropyl) adenine as a postexposure prophylaxis in blocking HIV-1 infection(2).

    Original languageEnglish (US)
    Pages (from-to)343-346
    Number of pages4
    JournalBioEssays
    Volume18
    Issue number5
    DOIs
    StatePublished - Jan 1 1996

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    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

    Cite this

    Sandstrom, P. A., & Folks, T. M. (1996). New strategies for treating AIDS. BioEssays, 18(5), 343-346. https://doi.org/10.1002/bies.950180502