Abstract
To date, the effective management of HIV-1 infection by anti-retroviral drugs has proved remarkably difficult to achieve. This is primarily due to the ease with which HIV-1 becomes resistant to drugs which initially may be very effective at blocking viral replication. In a recent issue of Science, two promising new AIDS treatments were reported. The first described the use of retroviral-type zinc finger structures found in the HIV-1 nucleocapsid protein as targets for antiretroviral drugs(1). The second demonstrated the feasibility of the reverse transcriptase inhibitor (R)-9-(2-phosphonylmethoxypropyl) adenine as a postexposure prophylaxis in blocking HIV-1 infection(2).
Original language | English (US) |
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Pages (from-to) | 343-346 |
Number of pages | 4 |
Journal | BioEssays |
Volume | 18 |
Issue number | 5 |
DOIs | |
State | Published - Jan 1 1996 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)