New strategies for treating AIDS

Paul A. Sandstrom, Thomas M. Folks

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations


    To date, the effective management of HIV-1 infection by anti-retroviral drugs has proved remarkably difficult to achieve. This is primarily due to the ease with which HIV-1 becomes resistant to drugs which initially may be very effective at blocking viral replication. In a recent issue of Science, two promising new AIDS treatments were reported. The first described the use of retroviral-type zinc finger structures found in the HIV-1 nucleocapsid protein as targets for antiretroviral drugs(1). The second demonstrated the feasibility of the reverse transcriptase inhibitor (R)-9-(2-phosphonylmethoxypropyl) adenine as a postexposure prophylaxis in blocking HIV-1 infection(2).

    Original languageEnglish (US)
    Pages (from-to)343-346
    Number of pages4
    Issue number5
    StatePublished - Jan 1 1996

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)


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