Neuropsiquiatria dos núcleos da base: Uma revisão

Translated title of the contribution: Neuropsychiatry of the basal ganglia: A review

Antônio Lúcio Teixeira, Francisco Cardoso

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

The basal ganglia are classically related to motor functions, being referred as the extra-pyramidal system. In the last years, studies suggest that the basal ganglia are involved in other dimensions of the human behavior. Five parallel circuits involving basal ganglia and frontal cortex have been described. Each of them controls a different set of behaviors that range from movements to cognitive and emotional actions. These circuits are assumed to facilitate cortically mediated behaviors by inhibiting conflicting behaviors. The neurobiological basis of a series of neuropsychiatric disorders, including obsessive-compulsive spectrum disorders, schizophrenia, depression and substance dependence, implies involvement of frontal-striatal circuits. Sydenham chorea is presented as an autoimmune model of different frontal-striatal circuits dysfunction.

Translated title of the contributionNeuropsychiatry of the basal ganglia: A review
Original languagePortuguese
Pages (from-to)153-158
Number of pages6
JournalJornal Brasileiro de Psiquiatria
Volume53
Issue number3
StatePublished - 2004
Externally publishedYes

Keywords

  • Basal ganglia
  • Cognitive control
  • Fronto-striatal circuits
  • Neuropsychiatric disorders
  • Sydenham chorea

ASJC Scopus subject areas

  • Psychiatry and Mental health

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